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Current management of symptomatic vesicoureteral reflux in pediatric kidney transplantation—A European survey among surgical transplant professionals.

Authors :
Zirngibl, Matthias
Weitz, Marcus
Luithle, Tobias
Tönshoff, Burkhard
Nadalin, Silvio
Buder, Kathrin
Aßfalg, Volker
Baccarani, Umberto
Beldi, Guido
Blanc, Thomas
Burkert, Jan
Desender, Liesbeth
Detry, Olivier
Ektov, Denis
Ferraresso, Mariano
Fischer, Lutz
García‐Aparicio, Luís
Garnier, Sarah
de Gier, Robert PE
van Heurn, Ernst WE
Source :
Pediatric Transplantation; Feb2024, Vol. 28 Issue 1, p1-14, 14p
Publication Year :
2024

Abstract

Background: Vesicoureteral reflux (VUR) is common in children and adolescents undergoing kidney transplantation (KTx) and may adversely affect allograft kidney function. Methods: To explore the current management of symptomatic native and allograft VUR in pediatric KTx recipients, an online survey was distributed to European surgical transplant professionals. Results: Surgeons from 40 pediatric KTx centers in 18 countries participated in this survey. Symptomatic native kidney VUR was treated before or during KTx by 68% of the centers (all/selected patients: 33%/67%; before/during KTx: 89%/11%), with a preference for endoscopic treatment (59%). At KTx, 90% favored an anti‐reflux ureteral reimplantation procedure (extravesical/transvesical approach: 92%/8%; preferred extravesical technique: Lich‐Gregoir [85%]). Management strategies for symptomatic allograft VUR included surgical repair (90%), continuous antibiotic prophylaxis (51%), bladder training (49%), or noninterventional surveillance (21%). Redo ureteral implantation and endoscopic intervention for allograft VUR were equally reported (51%/49%). Conclusions: This survey shows uniformity in some surgical aspects of the pediatric KTx procedure. However, with regard to VUR, there is a significant variation in practice patterns that need to be addressed by future well‐designed and prospective studies. In this way, more robust data could be translated into consensus guidelines for a more standardized and evidence‐based management of this common condition in pediatric KTx. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
13973142
Volume :
28
Issue :
1
Database :
Complementary Index
Journal :
Pediatric Transplantation
Publication Type :
Academic Journal
Accession number :
175282249
Full Text :
https://doi.org/10.1111/petr.14621