تأثیر تزریق ویتامین E سلنیوم بر عملکرد تولیدمثلی ، میانگین وزن تولد برهها و برخی فراسنجههای خون ی در میشهای مغانی هم زمان شده فحلی.

Introduction: Stimulation of ovulation using different methods can improves reproduction performance by increasing the proportion of ewes having twin ovulations and thereby increase lambing percentage. Estrus synchronization or the induction of estrus is a valuable management tool for increasing the pregnancy rate in ewes. It has been proposed that estrus synchronization can impose oxidative stress in animals and hence, supplying antioxidants at the time estrus synchronization could improve their fertility by decreasing the oxidative damage. Vitamin E and Se are important antioxidants and can prevent the cellular damage caused by free radicals and influence the reproductive performance of ewes and their lambs. The important roles of supplemental vitamin E and Se in sheep and goat reproduction and lamb survival have been intensively reviewed. The aim of this study was to investigate the effects of injecting estrus-synchronized Moghani ewes with vitamin E-Se on their reproductive performance, birth weight of lambs and some blood metabolites. Material and Methods: The experiment was carried out on 200 mature (2–5 years of age), non-lactating ewes with an average body weight 70 kg. The current study was performed in the non-breeding season under natural photoperiod environment. In the control group, only estrus synchronization was performed, but the second group was received two intramuscular (5 ml) injections of E-se (0.5 mg/mL of selenium as sodium selenite and 50 IU vitamin E as DL-α- tocopheryl) on the days of sponging and sponge removal. Synchronization of estrus was done by inserting intravaginal sponges for 14 days followed by 400 IU eCG at sponge withdrawal. Two days after sponge withdrawal, ewes were joined with fertile rams. At the beginning of the experiment, 20 ewes from each group were selected randomly and their blood was sampled. The first and second blood samplings were done before inserting intravaginal sponges and three weeks after ram exposure, respectively. Then, some blood plasma metabolites were determined. After parturition, reproductive traits were calculated in each group. The birth weight of lambs was recorded after parturition as well. The reproductive parameters were analyzed by ProcGenmod using SAS 9.2 in completely randomized design. The means of all reproductive traits were compared by using Chi-Square test. Born weight of lambs and blood metabolites concentration data were analyzed using the GLM procedure of SAS and P < 0.05 was considered as the significant level. Results and Discussion: The results showed that there was no significant effect of E-se on the estrus response and pregnancy rate in non-breeding season. Lambing rate in E-se treatment (88%) was higher (P < 0.05) than the control group (73%). Control group had lower fecundity rate (84%) than the treatment group (111%). In Ese-treated group, percentage of prolificacy was significantly different (P < 0.05) compared with control (126.1% vs 112.3%, respectively). Twinning rate in E-se groups was greater (P < 0.05) than the control (21.6% vs 12.3%, respectively). The birth weight of lambs was not significantly affected by E-Se administration compared with control. Glucose and cholesterol concentration of blood were significantly higher in group receiving E-se three weeks after mating (P < 0.05). Likely, the main reason of these contradictory results with the other researcher results develops from duration and time of E-Se use, dosage, source, and route of E-Se administration in pre-breeding ewes. Conclusion: In conclusion, using of vitamin E-Se caused improvement of reproductive efficiency of Moghani ewe in non-breeding season. [ABSTRACT FROM AUTHOR]