Wroclaw Medical University Researchers Advance Knowledge in Heart Failure (Spot urine sodium as a marker of urine dilution and decongestive abilities in acute heart failure).

Researchers from Wroclaw Medical University have conducted a study on acute heart failure (AHF) and the correlation between spot urine sodium concentrations (UNa+) and urine dilution. The study involved 50 AHF patients who received a standardized furosemide dose. The results showed that higher UNa+ levels were associated with higher urine dilution, and patients who were not chronically exposed to furosemide had a greater ability to dilute urine compared to chronic furosemide users. This research provides mechanistic insights into the decongestive abilities in AHF and highlights the importance of assessing sodium concentration and urine volume in the treatment of heart failure. [Extracted from the article]