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The Impact of Endometriosis on Pregnancy.

Authors :
Tsikouras, Panagiotis
Oikonomou, Efthimios
Bothou, Anastasia
Chaitidou, Penelopi
Kyriakou, Dimitrios
Nikolettos, Konstantinos
Andreou, Sotirios
Gaitatzi, Foteini
Nalbanti, Theopi
Peitsidis, Panagiotis
Michalopoulos, Spyridon
Zervoudis, Stefanos
Iatrakis, George
Nikolettos, Nikolaos
Source :
Journal of Personalized Medicine; Jan2024, Vol. 14 Issue 1, p126, 19p
Publication Year :
2024

Abstract

Despite the increased frequency of endometriosis, it remains one of the most enigmatic disorders regarding its effects on pregnancy. Endometriosis adversely affects both natural and assisted conception. Impaired folliculogenesis, which causes follicular dysfunction and low egg quality, as well as luteal phase problems, reduced fertilization, and abnormal embryogenesis, are some of the mechanisms advocated to explain reproductive dysfunction. There is a rising need for a comprehensive study of the potential negative consequences of this condition on pregnancy outcomes, including the postpartum period, as more women with a medical history of endometriosis become pregnant. Obstetrical complications (small for gestational age [SGA], cesarean section [CS], miscarriage, hemorrhage, low placental adhesion, and preterm delivery) are statistically elevated in women with endometriosis. Furthermore, ruptured ovarian endometrioma, appendicitis, intestinal perforation, and hemoperitoneum have been described in pregnancy. Obstetricians are largely unfamiliar with these complications, as they have not been thoroughly investigated. The development and pathogenesis of endometriosis is an important field of study and has not yet been fully elucidated. Finding these mechanisms is crucial for the development of new and more effective strategies to treat this condition. Endometriosis can have an impact on obstetric and neonatal outcomes of pregnancy, in addition to its potential effects on conception. To date, no additional monitoring is recommended for pregnancies with a history of endometriosis. However, more studies are urgently needed to assess the need for the tailored pregnancy monitoring of women with endometriosis. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
20754426
Volume :
14
Issue :
1
Database :
Complementary Index
Journal :
Journal of Personalized Medicine
Publication Type :
Academic Journal
Accession number :
175080196
Full Text :
https://doi.org/10.3390/jpm14010126