New Regenerative Medicine Study Findings Recently Were Reported by Researchers at Jahrom University of Medical Sciences (In Vitro Effect of Propofol On the Expression of Genes Involved In Inflammation and Apoptosis In Corneal Activated...).

Researchers at Jahrom University of Medical Sciences in Iran conducted a study on the effects of propofol on gene expression in corneal activated keratocytes (CAKs). The study found that propofol treatment at certain concentrations led to the downregulation of genes associated with inflammation (IL-1 beta and IL-6) and the upregulation of genes associated with cell regeneration (LIF). However, treatment with a higher concentration of propofol (50 mu M) resulted in the upregulation of a gene associated with fibrogenesis (TGF-beta). The study suggests that propofol could be used in the treatment of corneal stromal diseases and ocular regenerative medicine. [Extracted from the article]