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Pharmacokinetics of vitamin dosage forms: A complete overview.

Authors :
Sugandhi, Vrashabh V.
Pangeni, Rudra
Vora, Lalitkumar K.
Poudel, Sagun
Nangare, Sopan
Jagwani, Satveer
Gadhave, Dnyandev
Qin, Chaolong
Pandya, Anjali
Shah, Purav
Jadhav, Kiran
Mahajan, Hitendra S.
Patravale, Vandana
Source :
Food Science & Nutrition; Jan2024, Vol. 12 Issue 1, p48-83, 36p
Publication Year :
2024

Abstract

Vitamins are crucial for sustaining life because they play an essential role in numerous physiological processes. Vitamin deficiencies can lead to a wide range of severe health issues. In this context, there is a need to administer vitamin supplements through appropriate routes, such as the oral route, to ensure effective treatment. Therefore, understanding the pharmacokinetics of vitamins provides critical insights into absorption, distribution, and metabolism, all of which are essential for achieving the desired pharmacological response. In this review paper, we present information on vitamin deficiencies and emphasize the significance of understanding vitamin pharmacokinetics for improved clinical research. The pharmacokinetics of several vitamins face various challenges, and thus, this work briefly outlines the current issues and their potential solutions. We also discuss the feasibility of enhanced nanocarrierā€based pharmaceutical formulations for delivering vitamins. Recent studies have shown a preference for nanoformulations, which can address major limitations such as stability, solubility, absorption, and toxicity. Ultimately, the pharmacokinetics of pharmaceutical dosage forms containing vitamins can impede the treatment of diseases and disorders related to vitamin deficiency. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
20487177
Volume :
12
Issue :
1
Database :
Complementary Index
Journal :
Food Science & Nutrition
Publication Type :
Academic Journal
Accession number :
174976996
Full Text :
https://doi.org/10.1002/fsn3.3787