Back to Search
Start Over
Polypharmacy and Healthcare Service Use Among Prescription Opioid Poisoning Cases Age 50+.
- Source :
- Journal of Pharmacy Practice; Feb2024, Vol. 37 Issue 1, p151-161, 11p
- Publication Year :
- 2024
-
Abstract
- Objectives: To examine relationships between polypharmacy and level of healthcare service use among prescription opioid poisoning cases age 50 and older. Methods: Data came from the American Association of Poison Control Center's National Poison Data System, 2015-2020. We used multinomial logistic regression to examine the study questions. Results: Of the 77 946 cases with prescription opioid exposures, 64.5% were managed at a healthcare facility (HCF). Of HCF-managed cases, 41.2% were treated/evaluated and released and 21.3% and 37.5% were admitted for noncritical care and critical care, respectively. Medications for cardiovascular disease, benzodiazepines, other types of sedatives/hypnotics, antipsychotics, muscle relaxants, acetaminophen, and gabapentin were associated with increased risk of admission to both noncritical and critical care compared to treatment/evaluation and release. Acetaminophen use had the highest relative risk ratios (RRRs) for noncritical care (1.70, 95% CI = 1.51-1.91) and critical care (1.56, 95% CI = 1.39-1.76). Each additional medication/substance used was associated with 1.14 (95% CI = 1.11-1.17) and 1.19 (95% CI = 1.16-1.22) greater risk of noncritical and critical care admissions, respectively. Conclusions: Among older-adult poison control center cases for prescription opioid exposures, co-use of several commonly prescribed/used medicines was associated with increased risk of admissions to both noncritical and critical care units. Careful monitoring of medication use among older adults who use prescription opioids may reduce the risk of unintentional and intentional opioid poisoning. [ABSTRACT FROM AUTHOR]
- Subjects :
- DRUG toxicity
CONFIDENCE intervals
HEALTH facilities
MUSCLE relaxants
POLYPHARMACY
MULTIPLE regression analysis
ACETAMINOPHEN
MEDICAL care
CARDIOVASCULAR diseases
INAPPROPRIATE prescribing (Medicine)
BENZODIAZEPINES
DESCRIPTIVE statistics
CRITICAL care medicine
RESEARCH funding
OPIOID analgesics
TRANQUILIZING drugs
ANTIPSYCHOTIC agents
GABAPENTIN
OLD age
Subjects
Details
- Language :
- English
- ISSN :
- 08971900
- Volume :
- 37
- Issue :
- 1
- Database :
- Complementary Index
- Journal :
- Journal of Pharmacy Practice
- Publication Type :
- Academic Journal
- Accession number :
- 174943718
- Full Text :
- https://doi.org/10.1177/08971900221129656