Patent Application Titled "Use Of Brain Organoids And Single Cell Genomics To Understand And Treat Neurodevelopmental And Neuropsychiatric Disorders" Published Online (USPTO 20240002936).

A patent application titled "Use Of Brain Organoids And Single Cell Genomics To Understand And Treat Neurodevelopmental And Neuropsychiatric Disorders" has been published online. The patent application discusses the use of human brain organoids, which are models of the developing human brain, combined with single-cell profiling methods to study the cellular complexity and molecular mechanisms of neurodevelopmental and neuropsychiatric disorders, specifically autism spectrum disorder (ASD). The inventors propose methods for screening pathological mechanisms in neurodevelopmental disorders and testing the effects of therapeutic agents on the development of cortical neuronal lineages. The patent application provides insights into the genetic and molecular basis of ASD and offers potential avenues for understanding and treating these disorders. [Extracted from the article]