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Research from Albert Einstein College of Medicine in the Area of Acute Myeloid Leukemia Published (TMIGD2 is an orchestrator and therapeutic target on human acute myeloid leukemia stem cells).
- Source :
- Stem Cell Week; 1/23/2024, p1366-1366, 1p
- Publication Year :
- 2024
-
Abstract
- A recent study conducted by researchers at Albert Einstein College of Medicine has identified a potential therapeutic target for acute myeloid leukemia (AML). The study found that a protein called TMIGD2 is expressed by AML cells and plays a crucial role in the development and maintenance of the disease. Targeting TMIGD2 with monoclonal antibodies was shown to reduce leukemia burden in AML patient-derived xenograft models without affecting normal hematopoietic stem/progenitor cells. These findings provide a promising strategy for the treatment of AML. [Extracted from the article]
- Subjects :
- ACUTE myeloid leukemia
STEM cells
MYELOID leukemia
THERAPEUTICS
STEM cell research
Subjects
Details
- Language :
- English
- ISSN :
- 15371360
- Database :
- Complementary Index
- Journal :
- Stem Cell Week
- Publication Type :
- Periodical
- Accession number :
- 174889781