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DNA sensing and repair systems unexpectedly team up against cancer.
- Source :
- Nature; Jan2024, Vol. 625 Issue 7995, p457-458, 2p
- Publication Year :
- 2024
-
Abstract
- DNA in the cytoplasm can be a sign of abnormalities such as viral infections or cancer. A protein with a role in DNA-damage response was unexpectedly found to activate defences against the threats indicated by cytoplasmic DNA. The MRN protein complex helps to activate the enzyme cGAS. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00280836
- Volume :
- 625
- Issue :
- 7995
- Database :
- Complementary Index
- Journal :
- Nature
- Publication Type :
- Academic Journal
- Accession number :
- 174800745
- Full Text :
- https://doi.org/10.1038/d41586-023-03994-4