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Clinical Subtypes of Lone Atrial Fibrillation.
- Source :
- Pacing & Clinical Electrophysiology; Jul2005, Vol. 28 Issue 7, p630-638, 9p, 2 Diagrams, 6 Charts
- Publication Year :
- 2005
-
Abstract
- PATTON, K.K., et al.: Clinical Subtypes of Lone Atrial Fibrillation . Aims: In the face of increasing evidence of underlying genetic heterogeneity for lone atrial fibrillation (LAF), we undertook a clinical analysis of subjects to identify the phenotypic subsets of this arrhythmia. Methods and Results: We evaluated serial patients who presented with LAF between July 5, 2001 and December 19, 2003. Subjects underwent a standardized interview to elicit a detailed medical history, prior therapies, and precipitants of atrial fibrillation. The results of a physical exam, electrocardiogram and echocardiogram were reviewed. One hundred and eighty subjects with a mean age of 45 years (15–67 years) at the time of diagnosis were enrolled. The majority of patients originally presented with paroxysmal fibrillation (94%), and 7.8% progressed to permanent AF. Reported triggers for AF included sleeping (44%), exercise (36%), alcohol use (36%), and eating (34%). Women with LAF had distinct symptoms, triggers for episodic AF, and over one-fourth had an underlying rheumatologic condition. Several subsets of AF including familial AF (39%), exercise-induced AF (32%), and conduction system disease requiring pacemaker implantation (7%), were identified. Conclusions: Family history, exercise as a trigger of AF, and a history of a pacemaker identified subtypes of LAF. (PACE 2005; 28:630–638) [ABSTRACT FROM AUTHOR]
- Subjects :
- ATRIAL fibrillation
ATRIAL arrhythmias
GENETICS
DISEASES
ARRHYTHMIA
Subjects
Details
- Language :
- English
- ISSN :
- 01478389
- Volume :
- 28
- Issue :
- 7
- Database :
- Complementary Index
- Journal :
- Pacing & Clinical Electrophysiology
- Publication Type :
- Academic Journal
- Accession number :
- 17478476
- Full Text :
- https://doi.org/10.1111/j.1540-8159.2005.00161.x