Linkage and association between a CD4 gene polymorphism and IDDM in Danish IDDM patients. The Danish IDDM Epidemiology and Genetics Group, and The Danish Study Group of Diabetes in Childhood.

Examines whether CD4+ t-cells play a role in diabetes pathogenesis. T-cell response to antigen presentation; Evidence qualifying the CD4 gene as a candidate gene for diabetes; Transmission disequilibrium study; Contribution of the CD4 gene polymorphism to familial clustering.