Pulse electrochemical synaptic transistor for supersensitive and ultrafast biosensors.

The article discusses the development of a pulse electrochemical synaptic transistor for supersensitive and ultrafast biosensors. The transistor combines sensing and amplifying functions and utilizes the advantages of electrochemical transistors (ECTs) in terms of signal amplification, bionic ability, and mechanical flexibility. By pulsing the presynaptic input and setting the modulation potential near transconductance intersection, the transistor-based pH sensor achieves high sensitivity and ultrafast response time. The proposed synaptic sensing strategy eliminates transconductance fluctuation and reduces power consumption, offering a new paradigm for high-performance biosensors. The article also discusses the evaluation and optimization of pH sensors based on ECTs using PEDOT:BTB films, as well as the development of a high-performance pH sensor based on ECTs. The sensor utilizes a transconductance curve junction as a constant gate bias to improve detection sensitivity and linearity, and pulse excitation is used to reduce response time and power consumption. The proposed sensor exhibits ultrahigh sensitivity and achieves a record-fast response time. The article concludes by stating that the pulse electrochemical synaptic transistor shows promise for pH sensing in biological environments and may inspire future research in bioelectronics. [Extracted from the article]