Study Data from Air Force Medical University Update Understanding of Pharmaceutical Biology (Screening of Rosmarinic Acid From Salvia Miltiorrhizae Acting On the Novel Target Trpc1 Based On the 'homology Modelling-virtual Screening-molecular...).

A study conducted at Air Force Medical University in Xi'an, China, has identified rosmarinic acid (RosA) as a potential active component in Salvia miltiorrhizae, a traditional Chinese medicine used for the treatment of thoracic obstruction. The study focused on the role of RosA in targeting the transient receptor potential canonical channel 1 (TRPC1) for myocardial injury treatment. Through various experiments, the researchers found that RosA exhibited a high binding affinity to TRPC1 protein and showed potential in reducing TRPC1 protein levels and inhibiting TRPC1-mediated calcium influx injury. The study suggests that RosA may have promising applications in myocardial injury therapy. [Extracted from the article]