Findings from Roland Institute of Pharmaceutical Sciences in Anticancer Agents Reported (Bioanalysis of Anticancer Agents: Evaluating Lc-ms/ms Procedures With Greenness Metrics).

A recent report from the Roland Institute of Pharmaceutical Sciences in Odisha, India discusses the use of liquid chromatography-tandem mass spectrometry (LC-MS/MS) procedures in the bioanalysis of anticancer agents. The report highlights the importance of these procedures in therapeutic drug monitoring but also raises concerns about the environmental impact and safety risks associated with their routine application. The researchers conducted a comprehensive review of greenness metric tools and their applications in bioanalytical procedures, identifying six holistic greenness metrics that comply with the principles of green analytical chemistry. The report concludes by discussing the challenges and future possibilities for incorporating greenness assessment into existing workflows. [Extracted from the article]