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Comparison of endoscopic balloon dilation and surgery for duodenal stricture in patients with Crohn's disease.
- Source :
- Scandinavian Journal of Gastroenterology; Jan-Jun2024, Vol. 59 Issue 1, p39-45, 7p
- Publication Year :
- 2024
-
Abstract
- Few studies have compared endoscopic balloon dilation (EBD) and surgery in the treatment of duodenal stricture in patients with Crohn's disease (CD). We performed a retrospective study to compare the efficacy and safety among patients with CD-associated duodenal stricture treated with EBD or surgery from October 2013 to December 2021. Univariate and multivariate analyses were performed to evaluate factors associated with recurrence-free or surgery-free survival. A total of 48 eligible patients were included, including 30 patients treated with EBD only and 18 patients treated with surgery. Patients treated with surgery experienced more symptomatic improvement (100% vs. 63.33%, p = 0.003) and significantly longer recurrence-free survival (6.31 [IQR: 3.00–8.39] years vs. 2.96 [IQR: 1.06–5.42] years, p = 0.01) but suffered more postprocedural adverse events (16.67% vs. 0.74% per procedure, p = 0.001). In patients initially treated with EBD (n = 41), a total of 11 (26.83%) required subsequent surgical intervention. Younger age at CD diagnosis (HR = 0.90, 95% CI: 0.81–1.00, p = 0.04) was associated with a higher risk for subsequent surgery. Surgery for CD-associated duodenal strictures was associated with a longer recurrence-free survival. EBD was safe and effective with minimal postprocedural adverse events but led to a high frequency of recurrence. [ABSTRACT FROM AUTHOR]
- Subjects :
- CROHN'S disease
ENDOSCOPIC surgery
ENTEROSCOPY
SURGERY
Subjects
Details
- Language :
- English
- ISSN :
- 00365521
- Volume :
- 59
- Issue :
- 1
- Database :
- Complementary Index
- Journal :
- Scandinavian Journal of Gastroenterology
- Publication Type :
- Academic Journal
- Accession number :
- 174468870
- Full Text :
- https://doi.org/10.1080/00365521.2023.2250495