Kinetics study of metformin hydrochloride and hydroxychloroquine sulfate drugs from aqueous solutions onto (carrageenan/carboxy methyl cellulose-g-poly acrylic acid) hydrogel.

In this study, hydrogel of "Carrageenan with carboxy methyl cellulose-grafting-poly acrylic acid (CG/CMC-g-P(AA))" was used as the adsorbent for the removal of metformin hydrochloride MFC and hydroxychloroquine sulfate HCQ from aqueous solutions. In order to investigate the structure and morphology of the hydrogel, an FTIR as well as a field emission scanning electron microscope were utilized. The effect of equilibrium time was investigated, and it was determined that the adsorption of MFC and HCQ onto CG/CMC-g(AA) hydrogel reached equilibrium after 120 minutes. The removal percentage of metformin hydrochloride (MFC) and hydroxychloroquine sulfate (HCQ) by CG/CMC-g-P(AA) hydrogel were found to be 89.7% and 97.9%, at the same order. The adsorption kinetic result was well fitted to model second order, The data found that rate constants of the second order (MFC-G/CMC-g-P(AA)) system is much higher than that of (HCQ-CG/CMC-g-P(AA)) hydrogel. [ABSTRACT FROM AUTHOR]