Population mobility change for controlling the transmission of COVID-19: mobile phone data analysis in nine cities of China.

Mobility restriction measures were the main tools to control the spread of COVID-19, but the extent to which the mobility has decreased remained unsure. We investigated the change in local population mobility and its correlation with COVID-19 infections, using 1185 billion aggregated mobile phone data records in nine main cities in China from 10 January to 24 February 2020. The mobility fell by as much as 79.57% compared to the normal days in 2020 and by 58.13% compared to the same lunar period in 2019. The daily incidence of COVID-19 was significantly correlated with local daily mobility (R² = 0.77, P < 0.001). The instantaneous reproduction number R(t) declined by 3% when mobility was reduced by 10% in the GLM analysis (P < 0.05). Our study indicated that the decreased mobility level, driven by a mixture effect of holiday and public health interventions, could substantially reduce the transmission of COVID-19 to a low level. Our study could provide evidence of mobility restriction to control local transmission for other places facing COVID-19 outbreaks or potential next waves. [ABSTRACT FROM AUTHOR]