Studies from Yenepoya (Deemed to be University) Update Current Data on Tissue Engineering (Fabrication and characterizations of simvastatin-containing mesoporous bioactive glass and molybdenum disulfide scaffold for bone tissue engineering).

A recent study conducted by researchers at Yenepoya (Deemed to be University) in Karnataka, India, explores the development of a novel biomaterial composite scaffold for bone tissue engineering. The scaffold, made from a combination of poly (D, L-lactide-co-glycolide) (PLGA), mesoporous bioactive glass (MBG), molybdenum disulfide (MoS2), and simvastatin (Sim), aims to address the limitations of current bone grafting techniques. The researchers found that the fabricated scaffold showed promising results in terms of protein adsorption, water adsorption and retention, biodegradation, and bone mineral hydroxyapatite development. In vitro and in vivo studies also demonstrated the scaffold's biocompatibility and ability to stimulate bone regeneration. This research provides valuable insights into the potential of the PLGA-MBG-MoS2-Sim composite scaffold as a solution for bone grafting challenges. [Extracted from the article]