The effect of diabetic ketoacidosis in childhood on heart rate variability: Prospective study.

Objective: The study aims to investigate the changes caused by diabetic ketoacidosis (DKA) on heart rate variability (HRV). Material and Methods: This prospective study was conducted at a tertiary referral center. It is investigated patients with DKA under 18 years old between May 2016 and December 2016. 24-h rhythm Holter electrocardiography recorded during DKA and upward 72nd h after ketoacidosis. Results: A total of 18 patients with DKA were included in the study in the age range of 1 month–18 year. Repeat Holter electrocardiography recording in the patients took place within an average of 4.6±1.1 days. Heart rate change parameters were found to be shorter at the time of DKA. A statistically significant difference was observed between the values of HRV. Conclusion: It is an important factor affecting the development of cardiac autonomic neuropathy at acute blood glucose elevation such as DKA. [ABSTRACT FROM AUTHOR]