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Vitamin C Is Mandatory for the Tricarboxylic Acid Cycle Production of Antiinflammatory Itaconate.

Authors :
Soysal, Elif
Castellano, Elizabeth
Korkmaz, Aybike
Mullett, Steven J.
Kim-Campbell, Nahmah
Epperly, Michael
Wendell, Stacy
Kagan, Valerian E.
Bayır, Hülya
Source :
American Journal of Respiratory & Critical Care Medicine; 12/1/2023, Vol. 208 Issue 11, p1234-1238, 5p
Publication Year :
2023

Abstract

The article focuses on the essential role of vitamin C in the tricarboxylic acid cycle for the production of anti-inflammatory itaconate. Topics include the involvement of vitamin C in metabolic pathways, the anti-inflammatory properties of itaconate, and the potential implications for therapeutic interventions targeting redox balance.

Details

Language :
English
ISSN :
1073449X
Volume :
208
Issue :
11
Database :
Complementary Index
Journal :
American Journal of Respiratory & Critical Care Medicine
Publication Type :
Academic Journal
Accession number :
174024327
Full Text :
https://doi.org/10.1164/rccm.202304-0636LE