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Molecular Syringe for Cargo Photorelease: Red‐Light‐Triggered Supramolecular Hydrogel.
- Source :
- Chemistry - A European Journal; 11/21/2023, Vol. 29 Issue 65, p1-5, 5p
- Publication Year :
- 2023
-
Abstract
- Photochromic supramolecular hydrogels are versatile materials that show macroscopic effects upon irradiation, like liquefaction or shape changes. Here, we demonstrate a simple photochromic cyclic dipeptide (2,5‐diketopiperazine‐based) supergelator, composed of (S)‐lysine and an azobenzene analogue of phenylalanine, that forms supramolecular hydrogels even at 0.1 wt% loading. The gels can physically encapsulate cargo molecules and release them to the environment in a controllable manner upon irradiation with red light, thus working as a "molecular syringe". As the material is biocompatible and operational in the "therapeutic window" of light (>650 nm) that deeply penetrates soft human tissues, it is applicable to smart drug‐delivery systems. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 09476539
- Volume :
- 29
- Issue :
- 65
- Database :
- Complementary Index
- Journal :
- Chemistry - A European Journal
- Publication Type :
- Academic Journal
- Accession number :
- 173892820
- Full Text :
- https://doi.org/10.1002/chem.202302295