Synthesis of α‐Branched Enones via Chloroacylation of Terminal Alkenes.

Here, we show the conversion of unactivated alkenes into α‐branched enones via regioselective chloroacylation with acyl chlorides. The method relies upon the initial in situ generation of chlorine radicals directly from the acyl chloride precursor under cooperative nickel/photoredox catalysis. Subsequent HCl elimination provides enones and α,β‐unsaturated esters that are not accessible via the conventional acylation approaches that provide the other, linear constitutional isomer. [ABSTRACT FROM AUTHOR]