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Massive underrepresentation of Arabs in genomic studies of common disease.

Authors :
Bhattacharya, Romit
Chen, NingNing
Shim, Injeong
Kuwahara, Hiroyuki
Gao, Xin
Alkuraya, Fowzan S.
Fahed, Akl C.
Source :
Genome Medicine; 11/22/2023, Vol. 15 Issue 1, p1-5, 5p
Publication Year :
2023

Abstract

Arabs represent 5% of the world population and have a high prevalence of common disease, yet remain greatly underrepresented in genome-wide association studies, where only 1 in 600 individuals are Arab. We highlight the persistent and unaddressed underrepresentation of Arabs in genomic databases and discuss its impact on public health genomics and missed opportunities for biological discovery. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
1756994X
Volume :
15
Issue :
1
Database :
Complementary Index
Journal :
Genome Medicine
Publication Type :
Academic Journal
Accession number :
173805031
Full Text :
https://doi.org/10.1186/s13073-023-01254-8