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Pre-acquired CT-based attenuation correction with automated headrest removal for a brain-dedicated PET system.
- Source :
- Radiological Physics & Technology; Dec2023, Vol. 16 Issue 4, p552-559, 8p
- Publication Year :
- 2023
-
Abstract
- Attenuation correction (AC) is essential for quantitative positron emission tomography (PET) images. Attenuation coefficient maps (μ-maps) are usually generated from computed tomography (CT) images when PET-CT combined systems are used. If CT has been performed prior to PET imaging, pre-acquired CT can be used for brain PET AC, because the human head is almost rigid. This pre-acquired CT-based AC approach is suitable for stand-alone brain-dedicated PET, such as VRAIN (ATOX Co. Ltd., Tokyo, Japan). However, the headrest of PET is different from the headrest in pre-acquired CT images, which may degrade the PET image quality. In this study, we prepared three different types of μ-maps: (1) based on the pre-acquired CT, where namely the headrest is different from the PET system (μ-map-diffHr); (2) manually removing the headrest from the pre-acquired CT (μ-map-noHr); and (3) artificially replacing the headrest region with the headrest of the PET system (μ-map-sameHr). Phantom images by VRAIN using each μ-map were investigated for uniformity, noise, and quantitative accuracy. Consequently, only the uniformity of the images using μ-map-diffHr was out of the acceptance criteria. We then proposed an automated method for removing the headrest from pre-acquired CT images. In comparisons of standardized uptake values in nine major brain regions from the <superscript>18</superscript>F-fluoro-2-deoxy-D-glucose-PET of 10 healthy volunteers, no significant differences were found between the μ-map-noHr and the μ-map-sameHr. In conclusion, pre-acquired CT-based AC with automated headrest removal is useful for brain-dedicated PET such as VRAIN. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 18650333
- Volume :
- 16
- Issue :
- 4
- Database :
- Complementary Index
- Journal :
- Radiological Physics & Technology
- Publication Type :
- Academic Journal
- Accession number :
- 173804799
- Full Text :
- https://doi.org/10.1007/s12194-023-00744-z