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Models and methods to support the development of novel burn wound antimicrobial treatments.
- Source :
- Wounds UK; 2023, Vol. 19 Issue 4, p89-93, 5p
- Publication Year :
- 2023
-
Abstract
- Despite the advances in burn wound management, infection is a primary cause of morbidity, with infected burn wounds being responsible for 51% of burn related deaths. Because of the growing threat of multidrug resistant pathogens in burn injuries, novel therapeutic innovation remain important. This paper presents a comparison of common models and methods that support the development of novel burn wound antimicrobial treatments, of commonly available burn wound models 74% are performed in vivo, 23% are in vitro and just 3% use ex vivo tissue. The manufacturing of burn wound care products requires careful attention to materials, sterilisation, quality control, regulatory compliance and product design. By addressing these considerations systematically, manufacturers can successfully bring innovation solutions to the burn wound market while ensuring patient safety and product quality. [ABSTRACT FROM AUTHOR]
- Subjects :
- BIOLOGICAL models
IN vitro studies
WOUND healing
IN vivo studies
HEALTH services administration
BURNS & scalds
GOVERNMENT regulation
INFLAMMATION
ANTI-infective agents
REGULATORY approval
CREATIVE ability
BIOFILMS
HUMAN services programs
CYTOCHEMISTRY
INFECTION control
QUALITY assurance
COMMERCIAL product evaluation
STERILIZATION (Disinfection)
WOUND care
Subjects
Details
- Language :
- English
- ISSN :
- 17466814
- Volume :
- 19
- Issue :
- 4
- Database :
- Complementary Index
- Journal :
- Wounds UK
- Publication Type :
- Academic Journal
- Accession number :
- 173645402