Improved Diagnostics, Treatment and Follow-up of Acute Exacerbation of Chronic Obstructive Pulmonary Disease (COPEXNOR).

The document provides information about two clinical trials aimed at improving the diagnosis and treatment of acute exacerbations of chronic obstructive pulmonary disease (COPD). The first trial, NCT06105814, focuses on the use of antibiotics in treating exacerbations and aims to determine the most effective approach for identifying the microbiological cause of exacerbations. The second trial, called COPEXNOR, aims to evaluate the use of rapid diagnostics in patients with COPD exacerbation and respiratory tract infections. It plans to compare standard microbiological diagnostics with a rapid diagnostic platform called FilmArray. Both trials aim to guide antibiotic use and reduce the overuse of antibiotics to combat antimicrobial resistance. [Extracted from the article]