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Effectiveness of mindfulness‐based interventions on mental, cognitive outcomes and neuroplastic changes in older adults with mild cognitive impairment: A systematic review and meta‐analysis.
- Source :
- Journal of Advanced Nursing (John Wiley & Sons, Inc.); Dec2023, Vol. 79 Issue 12, p4489-4505, 17p
- Publication Year :
- 2023
-
Abstract
- Aims: To evaluate the effectiveness of mindfulness‐based interventions (MBIs) on mental and cognitive outcomes including, anxiety, depression, attention, memory, global cognition and neuroplastic changes in older adults with mild cognitive impairment (MCI). Design: Systematic review and meta‐analysis. Data source: A three‐step search strategy was conducted on eight electronic databases, grey literature and reference lists from inception to February 2022. Review methods: Randomized controlled trials (RCTs) examining MBIs on older adults with MCI were screened and assessed for risk of bias using the Cochrane Risk of Bias Tool. Meta‐analysis was conducted using RevMan using a random‐effect model. Narrative synthesis was performed for studies where results could not be pooled statistically. Results: Ten RCTs were included in the review. Results suggested that right frontal parietal and left inferior temporal gyrus of the brain showed increased cortical thickness after receiving MBIs. There were significant interaction effects for global efficiency and significant interactions in the insular and gyrus regions. Functional connectivity between the posterior cingulate cortex, bilateral medial prefrontal cortex and left hippocampus were increased in participants undergoing MBIs. Nevertheless, meta‐analysis showed non‐significant pooled effects, favouring control groups on anxiety, depression, attention, memory and global cognition. Conclusion: This review suggested the potential effects of MBIs in improving cortical thickness and connectivity in regions associated with memory and attention. Nevertheless, the effects of MBIs compared to active control groups on depression, anxiety, attention, memory and global cognition are inconclusive due to the lack of studies and non‐significant results. Impact: The review advocates for more rigorous studies with larger sample size and utilizing wait‐list controls to evaluate the effects of MBIs. MBIs can be considered as an adjunct with other therapies to further enhance the effect on psychological and cognitive outcomes for older adults with MCI. No Patient or Public Contribution as this is a meta‐analysis. [ABSTRACT FROM AUTHOR]
- Subjects :
- MINDFULNESS
MEMORY
ONLINE information services
PSYCHOLOGY information storage & retrieval systems
CINAHL database
MEDICAL databases
PREFRONTAL cortex
META-analysis
MEDICAL information storage & retrieval systems
HIPPOCAMPUS (Brain)
MILD cognitive impairment
SYSTEMATIC reviews
NEUROPLASTICITY
COGNITION
FUNCTIONAL connectivity
TREATMENT effectiveness
INSULAR cortex
MENTAL depression
ATTENTION
ANXIETY
MEDLINE
DATA analysis software
GREY literature
EVALUATION
OLD age
Subjects
Details
- Language :
- English
- ISSN :
- 03092402
- Volume :
- 79
- Issue :
- 12
- Database :
- Complementary Index
- Journal :
- Journal of Advanced Nursing (John Wiley & Sons, Inc.)
- Publication Type :
- Academic Journal
- Accession number :
- 173517103
- Full Text :
- https://doi.org/10.1111/jan.15720