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Expression of miR-203 and its target genes in condyloma acuminatum and their relationships with clinical recurrence.
- Source :
- Future Virology; Sep2023, Vol. 18 Issue 13, p855-863, 9p
- Publication Year :
- 2023
-
Abstract
- Aim: To examine the expression of miR-203 and its target genes survivin and p63 in condyloma acuminatum (CA) and to determine their relationships with clinical recurrence. Methods: Case and control groups were assessed for general data and the expression levels of miR-203, survivin and p63. The case group received carbon dioxide laser treatment, had a 3-month follow-up period, and was then divided into recurrence and non-recurrence groups. The relevant data were analyzed using SPSS v. 25.0 software. Results:miR-203 was identified as an independent protective factor against the recurrence of CA, while wart number, survivin and p63 were independent risk factors for CA recurrence. Conclusion:miR-203 could be a specific clinical bioindicator for the prognosis and recurrence of CA. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 17460794
- Volume :
- 18
- Issue :
- 13
- Database :
- Complementary Index
- Journal :
- Future Virology
- Publication Type :
- Academic Journal
- Accession number :
- 173494342
- Full Text :
- https://doi.org/10.2217/fvl-2023-0086