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Revisiting Asthma Obstructive Sleep Apnea Overlap: Current Knowledge and Future Needs.
- Source :
- Journal of Clinical Medicine; Oct2023, Vol. 12 Issue 20, p6552, 18p
- Publication Year :
- 2023
-
Abstract
- Asthma and obstructive sleep apnea are highly prevalent conditions with a high cost burden. In addition to shared risk factors, existing data suggest a bidirectional relationship between asthma and OSA, where each condition can impact the other. Patients with asthma often complain of sleep fragmentation, nocturnal asthma symptoms, daytime sleepiness, and snoring. The prevalence of OSA increases with asthma severity, as evidenced by multiple large studies. Asthma may lower the threshold for arousal in OSA, resulting in the hypopnea with arousal phenotype. Epidemiologic studies in adults have shown that OSA is associated with worse asthma severity, increased frequency of exacerbation, and poor quality of life. The current literature assessing the relationship among OSA, asthma, and CPAP therapy is heavily dependent on observational studies. There is a need for randomized controlled trials to minimize the interference of confounding shared risk factors. [ABSTRACT FROM AUTHOR]
- Subjects :
- SLEEP apnea syndromes
HYPERSOMNIA
ASTHMA
ASTHMATICS
RANDOMIZED controlled trials
Subjects
Details
- Language :
- English
- ISSN :
- 20770383
- Volume :
- 12
- Issue :
- 20
- Database :
- Complementary Index
- Journal :
- Journal of Clinical Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 173320051
- Full Text :
- https://doi.org/10.3390/jcm12206552