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LILRB3 suppresses immunity in glioma and is associated with poor prognosis.
- Source :
- Clinical & Translational Medicine; Oct2023, Vol. 13 Issue 10, p1-6, 6p
- Publication Year :
- 2023
-
Abstract
- Based on immunohistochemistry (IHC) staining, only 5% of glioma tissues with low LILRB3 expression exhibited high PD-1 expression, while both low and high PD-1 expression was observed in high-LILRB3-expression samples (Figure 3D,E and Figure S7A). Samples with high expression or median expression of LILRB3 are classified into high LILRB3 group for Chi-square analysis. This finding is in line with previous reports demonstrating that LILRB3 can interact with SHP-1 in 293T cells.[10] Moreover, high expression of APOE shows a lower T cell activation expression pattern in GBM (Figure 2Q). [Extracted from the article]
Details
- Language :
- English
- ISSN :
- 20011326
- Volume :
- 13
- Issue :
- 10
- Database :
- Complementary Index
- Journal :
- Clinical & Translational Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 173280760
- Full Text :
- https://doi.org/10.1002/ctm2.1396