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Synthesis, Characterization and Biological Properties of Mn (II) and Cu (II) Complexes with Sulfonamide and Imidazole Derivatives: Genotoxicity, ADME Profile, and Molecular Docking Studies.

Authors :
Bouchoucha, Afaf
Amine Bourouai, Mohamed
Si Larbi, Karima
Merazka, Hadjer
Boulanouar, Salah
Djabbar, Safia
Source :
ChemistrySelect; 10/26/2023, Vol. 8 Issue 40, p1-21, 21p
Publication Year :
2023

Abstract

The synthesis, characterization, and comparative biological properties of manganese (II) and copper (II) complexes formed with two heterocyclic ligands used in the pharmaceutical field are reported. The characterization of the metal complexes involved elemental analysis, FAB mass spectroscopy, ESR, FTIR, UVā€Visible spectroscopy, and conductometry. The spectroscopic data allowed the determination of the coordination mode and the geometry of all the coordination compounds. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
23656549
Volume :
8
Issue :
40
Database :
Complementary Index
Journal :
ChemistrySelect
Publication Type :
Academic Journal
Accession number :
173230915
Full Text :
https://doi.org/10.1002/slct.202302779