Study Findings on Chronic Periodontitis Detailed by Researchers at Peking Union Medical College Hospital (Proteomic and single-cell analysis shed new light on the anti-inflammatory role of interferonb in chronic periodontitis).

Keywords: Chronic Periodontitis; Connective Tissue Cells; Cytokines; Genetics; Health and Medicine; Immunology; Intercellular Signaling Peptides and Proteins; Interferons; Macrophages; Mononuclear Phagocyte System; Mouth Diseases and Conditions; Myeloid Cells; Periodontal Diseases and Conditions; Periodontitis; Phagocytes; Proteomics; Stomatognathic Diseases and Conditions EN Chronic Periodontitis Connective Tissue Cells Cytokines Genetics Health and Medicine Immunology Intercellular Signaling Peptides and Proteins Interferons Macrophages Mononuclear Phagocyte System Mouth Diseases and Conditions Myeloid Cells Periodontal Diseases and Conditions Periodontitis Phagocytes Proteomics Stomatognathic Diseases and Conditions 5768 5768 1 10/24/23 20231027 NES 231027 2023 OCT 27 (NewsRx) -- By a News Reporter-Staff News Editor at Health & Medicine Week -- Current study results on chronic periodontitis have been published. It is also found that macrophage phenotype transitions in periodontitis involve the release of higher levels of IFNb, ISG15, and IL10 by the anti-inflammatory M2 macrophage phenotype compared to the pro-inflammatory M1 phenotype and myeloid-derived suppressor cells (MDSCs).". [Extracted from the article]