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Effects of Developmental Lead and Phthalate Exposures on DNA Methylation in Adult Mouse Blood, Brain, and Liver Identifies Tissue- and Sex-Specific Changes with Implications for Genomic Imprinting (Updated October 10, 2023).
- Source :
- Drug Week; 10/27/2023, p663-663, 1p
- Publication Year :
- 2023
-
Abstract
- DMRs were enriched in the imprinting control regions (ICRs) of Gnas and Grb10, with 15 and 17 ICR-located DMRs across cortex, blood, and liver in each gene, respectively. An analysis of GO terms associated with DMR-containing genes identified imprinted genes to be impacted by both Pb and DEHP exposure. [Extracted from the article]
Details
- Language :
- English
- ISSN :
- 15316440
- Database :
- Complementary Index
- Journal :
- Drug Week
- Publication Type :
- Periodical
- Accession number :
- 173087173