Back to Search
Start Over
Type of intracranial hemorrhage after endovascular stroke treatment: association with functional outcome.
- Source :
- Journal of NeuroInterventional Surgery; Oct2023, Vol. 15 Issue 10, p971-976, 7p
- Publication Year :
- 2023
-
Abstract
- Background Intracranial hemorrhage (ICH) is a frequent complication after endovascular stroke treatment. Objective To assess the association of the occurrence and type of ICH after endovascular treatment (EVT) with functional outcome. Methods We analyzed data from the MR CLEANNO IV and MR CLEAN- MED trials. Both trials included adult patients with ischemic stroke with a large vessel occlusion in the anterior circulation, who were eligible for EVT. ICH was classified (1) as asymptomatic or symptomatic (concomitant neurological deterioration of ≥4 points on the NIHSS, or ≥2 points on 1 NIHSS item), and (2) according to the Heidelberg Bleeding Classification. We used multivariable ordinal logistic regression analyses to assess the association of the occurrence and type of ICH with the modified Rankin Scale score at 90 days. Results Of 1017 included patients, 331 (33%) had an asymptomatic ICH, and 90 (9%) had a symptomatic ICH. Compared with no ICH, both asymptomatic (adjusted common OR (acOR)=0.76; 95% CI 0.58 to 0.98) and symptomatic (acOR=0.07; 95% CI 0.04 to 0.14) ICH were associated with worse functional outcome. In particular, isolated parenchymal hematoma type 2 (acOR=0.37; 95% CI 0.14 to 0.95), combined parenchymal hematoma with hemorrhage outside infarcted brain tissue (acOR=0.17; 95% CI 0.10 to 0.30), and combined hemorrhages outside infarcted brain tissue (acOR=0.14; 95% CI 0.03 to 0.74) were associated with worse functional outcome than no ICH. Strength of the association of ICH with functional outcome depends on the type of ICH. Although the association is stronger for symptomatic ICH, asymptomatic ICH after EVT is also associated with worse functional outcome. [ABSTRACT FROM AUTHOR]
- Subjects :
- STATISTICS
SCIENTIFIC observation
CEREBRAL hemorrhage
CONFIDENCE intervals
INTRACRANIAL hemorrhage
MULTIPLE regression analysis
REGRESSION analysis
TREATMENT effectiveness
SUBARACHNOID hemorrhage
COMPARATIVE studies
DESCRIPTIVE statistics
SUBDURAL hematoma
RESEARCH funding
ENDOVASCULAR surgery
DATA analysis
Subjects
Details
- Language :
- English
- ISSN :
- 17598478
- Volume :
- 15
- Issue :
- 10
- Database :
- Complementary Index
- Journal :
- Journal of NeuroInterventional Surgery
- Publication Type :
- Academic Journal
- Accession number :
- 173040247
- Full Text :
- https://doi.org/10.1136/jnis-2022-019474