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Neutrophil-to-Lymphocyte ratio and Monocyte-to-HDL ratio as a Biomarker of Urolithiasis.

Authors :
Butt, Afifa Jamil
Khawar, Muhammad Babar
Afzal, Ali
Bhalli, Asmat ullah
Hashmi, Muhammad Abu Talha Safdar
Afzal, Nimra
Hamid, Syeda Eisha
Shahzaman, Sara
Habiba, Ume
Shah, Syed Shakeel
Source :
Comparative Clinical Pathology; Oct2023, Vol. 32 Issue 5, p783-788, 6p
Publication Year :
2023

Abstract

Kidney stones are associated with increased chances of chronic kidney disorders, kidney failure, diabetes, hypertension, and cardiovascular disorders globally. This case–control study is designed to investigate the fluctuations in neutrophil-to-lymphocyte ratio (NLR) and monocyte-to-high-density lipid (HDL) ratio by comparing healthy subjects with cases suffering from kidney stones. Hematological and biochemical assays from 117 blood samples of cases and 117 control, collected between October 2021 to June 2022, were inferred by applying statistical tests. After t-test, various hematological parameters of diseased and control samples showed significant differences which comprise hemoglobin, neutrophils, lymphocytes, NLR, eosinophils, MCV, MCHC, RBCs, WBCs, and monocytes. Our investigation gives evidence of the differentiation of kidney stone patients because of the CBC and lipid profile results. These results can be utilized as a promising indicator for the analysis of kidney stones. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
16185641
Volume :
32
Issue :
5
Database :
Complementary Index
Journal :
Comparative Clinical Pathology
Publication Type :
Academic Journal
Accession number :
172916880
Full Text :
https://doi.org/10.1007/s00580-023-03488-9