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Diagnostic and Management of Emphysematous Hepatitis with Emphasis on Biopathology.

Authors :
Porez, Déborah
Kallel, Hatem
Dobian, Succes
Gerbert-Ferrendier, Timotée
Nacher, Mathieu
Djossou, Félix
Demar, Magalie
Amroun, Hakim
Zappa, Magaly
Drak Alsibai, Kinan
Source :
Microorganisms; Sep2023, Vol. 11 Issue 9, p2137, 11p
Publication Year :
2023

Abstract

Emphysematous hepatitis is a rare infectious disease, which corresponds to the presence of gas in the liver, without collection and after exclusion of vascular origin. This entity belongs to the group of emphysematous infections, whose physiopathology seems to be linked to the presence of unbalanced diabetes and to bacterial fermentation, leading to the production of gas within the liver parenchyma. Very few cases of emphysematous hepatitis have been described in the literature, and most of them had a rapidly fatal course. In this manuscript, we report the case of a 59-year-old man with emphysematous hepatitis due to wild-type Klebsiella pneumoniae that was successfully managed by surgery, and we perform a review of the literature to describe the clinical and biopathological aspects of this rare hepatic disease. Our manuscript underlines the need to perform biological and histopathological sampling to better understand the pathophysiology of this rare entity. The causes and mechanisms of emphysematous hepatitis, which seem to be multiple, lead us to believe that it is a syndrome rather than a simple infectious disease. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
20762607
Volume :
11
Issue :
9
Database :
Complementary Index
Journal :
Microorganisms
Publication Type :
Academic Journal
Accession number :
172413014
Full Text :
https://doi.org/10.3390/microorganisms11092137