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Expert consensus to optimize the management of older adult patients with advanced EGFR-mutated non-small cell lung cancer.

Authors :
Nadal, Ernest
Oré-Arce, Martín
Remon, Jordi
Bernabé-Caro, Reyes
Covela-Rúa, Marta
de Castro-Carpeño, Javier
Massutí-Sureda, Bartomeu
Guillot-Morales, Mónica
Majem, Margarita
Maestu-Maiques, Inmaculada
Morilla-Ruíz, Idoia
Gironés, Regina
Source :
Clinical & Translational Oncology; Nov2023, Vol. 25 Issue 11, p3139-3151, 13p
Publication Year :
2023

Abstract

Lung cancer (LC) is associated with ageing, with the average age of affected individuals being approximately 70 years. However, despite a higher incidence and prevalence among older people, the older adult population is underrepresented in clinical trials. For LC with Epidermal Growth Factor Receptor (EGFR) mutations, there is no clear association of this mutation with age. Geriatric assessments (GAs) and a multidisciplinary approach are essential for defining the optimal treatment. In this consensus, a group of experts selected from the Oncogeriatrics Section of the Spanish Society of Medical Oncology (Sección de Oncogeriatría de la Sociedad Española de Oncología Médica—SEOM), the Spanish Lung Cancer Group (Grupo Español de Cáncer de Pulmón—GECP) and the Association for Research on Lung Cancer in Women (Asociación para la Investigación del Cáncer de Pulmón en Mujeres—ICAPEM) evaluate the scientific evidence currently available and propose a series of recommendations to optimize the management of older adult patients with advanced LC with EGFR mutations. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
1699048X
Volume :
25
Issue :
11
Database :
Complementary Index
Journal :
Clinical & Translational Oncology
Publication Type :
Academic Journal
Accession number :
172284513
Full Text :
https://doi.org/10.1007/s12094-023-03286-3