Assignment<FOOTREF></FOOTREF> of the equine colony stimulating factor 1 receptor gene (CSF1R) to equine chromosome 14q15→q16 (ECA14q15→q16) by in situ hybridization and radiation hybrid panel mapping.

The article reports that the receptor of the macrophage colony-stimulating factor 1 (CSF1R) belongs to a subfamily of receptor tyrosine kinases. The CSF1R gene is in close vicinity to the PDGFR1 gene which is located only a few hundred basepairs proximal in a head-to-tail orientation. Hampe et al. (1989) demonstrated that the human CSF1R gene consists of 21 small exons interrupted by introns ranging in size from 6.3 to less than 0.1 kb. Mutations in the CSF1R gene have been shown to be causative for a number of hereditary diseases and neoplastic transformations.