Back to Search Start Over

Should mild obstructive sleep apnoea be treated? A systematic review from the standpoint of disease progression.

Authors :
Fong, P Y
Tay, Z Y
Soh, R Y
Fook, S M C
Li, H H
Phua, C Q
Source :
Journal of Laryngology & Otology; Aug2023, Vol. 137 Issue 8, p828-839, 12p
Publication Year :
2023

Abstract

Objective: This study was a systematic review to investigate the progression of untreated obstructive sleep apnoea in order to evaluate whether mild obstructive sleep apnoea should be treated from the standpoint of disease progression. Method: The database search study outcomes that were collected included Apnea Hypopnea Index and Respiratory Disturbance Index. A meta-analysis of obstructive sleep apnoea severity over time intervals was performed. Results: A total of 17 longitudinal studies and 1 randomised, controlled trial were included for review. For patients with mild obstructive sleep apnoea, mean pre-study and post-study Apnea Hypopnea Index was 5.21 and 8.03, respectively, over a median interval of 53.1 months. In patients with moderate to severe obstructive sleep apnoea, mean pre-study and post-study Apnea Hypopnea Index was 28.9 and 30.3, respectively, over a median interval of 57.8 months. Predictors for disease progression in mild obstructive sleep apnoea are patients aged less than 60 years and those with a baseline body mass index less than 25. Conclusion: Mild obstructive sleep apnoea progression is observed, but it does not appear to reach any clinically significant progression to moderate or severe obstructive sleep apnoea. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
00222151
Volume :
137
Issue :
8
Database :
Complementary Index
Journal :
Journal of Laryngology & Otology
Publication Type :
Academic Journal
Accession number :
170724405
Full Text :
https://doi.org/10.1017/S0022215122002419