Kinematic Analysis of Rat Motion After Spinal Cord Injury.

To evaluate and compare the gait of rats in the control group with spinal cord injury, when treated with methylprednisolone and when using methylprednisolone in a polymer composition, a video motion analysis method was used. To assess the mobility of the limb after SCI, foot movement trajectories were constructed to determine the volume of limb movement and the maximum point of foot elevation. To calculate the volume of movement, the coordinates of the sacrum at the beginning of movement and the coordinates of the foot at the beginning of movement were determined. Our results showed the ability of rats after spinal cord injury during treatment with methylprednisolone to maintain lateral stability during locomotion. The article presents a mathematical formulation of the definition of kinematic parameters, which makes it possible to accelerate the diagnosis of the disease and individualize treatment. The presented methods are as general as possible, which allows them to be used for various experimental schemes. [ABSTRACT FROM AUTHOR]