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Innovative Metal-Organic Frameworks for Targeted Oral Cancer Therapy: A Review.

Authors :
Mousavi, Seyyed Mojtaba
Hashemi, Seyyed Alireza
Fallahi Nezhad, Fatemeh
Binazadeh, Mojtaba
Dehdashtijahromi, Milad
Omidifar, Navid
Ghahramani, Yasamin
Lai, Chin Wei
Chiang, Wei-Hung
Gholami, Ahmad
Source :
Materials (1996-1944); Jul2023, Vol. 16 Issue 13, p4685, 27p
Publication Year :
2023

Abstract

Metal-organic frameworks (MOFs) have proven to be very effective carriers for drug delivery in various biological applications. In recent years, the development of hybrid nanostructures has made significant progress, including developing an innovative MOF-loaded nanocomposite with a highly porous structure and low toxicity that can be used to fabricate core-shell nanocomposites by combining complementary materials. This review study discusses using MOF materials in cancer treatment, imaging, and antibacterial effects, focusing on oral cancer cells. For patients with oral cancer, we offer a regular program for accurately designing and producing various anticancer and antibacterial agents to achieve maximum effectiveness and the lowest side effects. Also, we want to ensure that the anticancer agent works optimally and has as few side effects as possible before it is tested in vitro and in vivo. It is also essential that new anticancer drugs for cancer treatment are tested for efficacy and safety before they go into further research. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
19961944
Volume :
16
Issue :
13
Database :
Complementary Index
Journal :
Materials (1996-1944)
Publication Type :
Academic Journal
Accession number :
164917964
Full Text :
https://doi.org/10.3390/ma16134685