Airborne allergic contact dermatitis to artichoke (Cynara cardunculus L.) in a greengrocer.

In common with many other members of this family, they contain sesquiterpene lactones (SLs) as allergens.[2] CASE REPORT A 35-year-old male greengrocer was referred from the Emergency Ward for severe "angioedema-like" periorbital eczema (Figure 1). Keywords: airborne ACD; artichoke; case report; Compositae; Cynara cardunculus; occupational; sesquiterpene lactones EN airborne ACD artichoke case report Compositae Cynara cardunculus occupational sesquiterpene lactones 120 122 3 07/11/23 20230801 NES 230801 Artichokes ( I Cynara cardunculus i L.) are known to cause allergic contact dermatitis (ACD) on exposed skin by direct contact but also by airborne spread.[[1], [3]] Formerly known as I Cynara scolymus i L., or I Cynara cardunculus i subsp. I scolymus i (L.) Hegi, or I Cynara cardunculus i var. I scolymus i (L.) Benth., or by other names all now regarded as synonyms, these vegetables belong the Compositae (or Asteraceae) family. The main SLs allergens in artichokes are reported to be cynaropicrin, grosheimin and its derivative 8-deoxy-11,13-dihydroxygrosheimin[2] but the specific SLs responsible for ACD to artichoke and their possible co- or cross-reactivity with other well-known SLs allergens remain unknown. [Extracted from the article]