Effects of 3-Glucosaminoglycan Sulfate on Hemorheologic Parameters in Hyperlipidemic Peripheral Vascular 1 Disease (PVD) Patients: A Preliminary Double-Blind Crossover Study.

The effects of 3-glucosaminoglycan sulfate on lipids and the hemorheologic parameters were observed in a preliminary double-blind crossover study in 30 hyperlipidemic peripheral vascular disease (PYD) patients. Parenteral administration of the test drug was associated with a reduction in serum lipids, especially in triglyceride levels, and a lowering of fibrinogen, plasma viscosity, and whole blood viscosity levels. These effects justify the drug's use in the treatment of PYD, especially when associated with hypertriglyceridemia and hemorheologic disturbances. [ABSTRACT FROM AUTHOR]