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DEX‐Induced SREBF1 Promotes BMSCs Differentiation into Adipocytes to Attract and Protect Residual T‐Cell Acute Lymphoblastic Leukemia Cells After Chemotherapy (Adv. Sci. 19/2023).
- Source :
- Advanced Science; 7/6/2023, Vol. 10 Issue 19, p1-1, 1p
- Publication Year :
- 2023
-
Abstract
- DEX-Induced SREBF1 Promotes BMSCs Differentiation into Adipocytes to Attract and Protect Residual T-Cell Acute Lymphoblastic Leukemia Cells After Chemotherapy (Adv. Sci. 19/2023) Last, an SREBF1 inhibitor demonstrates superior improvement on therapeutic effect of dexamethason by reducing adipogenesis and provides a feasible strategy to solve the dilemma of recurrence. B T-Cell Acute Lym-phoblastic Leukemia b In article number 2205854, Jingjing Ye, Min Ji, Chunyan Ji, and co-workers observed aberrant adipogenesis in the bone marrow of chemotherapy-treated T-cell acute lymphoblastic leukemia (T-ALL) patients, and the differentiated-adipocytes attract and support residual T-ALL cells. [Extracted from the article]
Details
- Language :
- English
- ISSN :
- 21983844
- Volume :
- 10
- Issue :
- 19
- Database :
- Complementary Index
- Journal :
- Advanced Science
- Publication Type :
- Academic Journal
- Accession number :
- 164763712
- Full Text :
- https://doi.org/10.1002/advs.202370125