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Associated factors for postoperative delirium following major abdominal surgery: A systematic review and meta‐analysis.
- Source :
- International Journal of Geriatric Psychiatry; Jun2023, Vol. 38 Issue 6, p1-12, 12p
- Publication Year :
- 2023
-
Abstract
- Objectives: Postoperative delirium (POD) is a common postsurgical complication. The early identification of its risk factors is the first step toward reducing POD. The predictive factors for POD in patients after major abdominal surgery remain obscure. Therefore, this meta‐analysis aimed to comprehensively summarize the risk factors of POD after major abdominal surgery. Methods: POD studies published between January, 1900 and June 2022 were obtained by searching PubMed, Cochrane Library, Web of Science, Embase, and Medline. Two authors independently reviewed the studies to extract the risk factors and assessed the quality of related articles using the Newcastle‐Ottawa Scale. Data were recorded, and a meta‐analysis was performed using Review Manager version 5.4.1. Results: Ten studies including total 2900 patients undergoing major abdominal surgery, were eligible for analysis, 608 of whom developed POD, for a cumulative incidence of 21%. This pooled analysis suggested the statistically significant risk factors for POD were age, higher American Society of Anesthesiologists grade, lower preoperative Mini‐Mental State Examination score, cognitive impairment, preoperative Katz‐ADL score <6, preoperative and postoperative hypoalbuminemia, lower preoperative insulin‐like growth factor‐1 levels, and longer duration of anesthesia. Conclusion: POD is common in patients undergoing major abdominal surgery. This meta‐analysis identified risk factors that may aid the early detection of POD and play a prominent role in preventing POD. Key points: Our report was the first to comprehensively summarize the related risk factors for postoperative delirium (POD) after major abdominal surgery; the results of this pooled analysis suggested the statistically significant risk factors for POD were age, higher American Society of Anesthesiologists grade, lower preoperative Mini‐Mental State Examination score, cognitive impairment, preoperative Katz‐ADL score <6, preoperative and postoperative hypoalbuminemia, lower preoperative insulin‐like growth factor‐1 levels, and longer durations of anesthesia, which may better predict the risk of POD. [ABSTRACT FROM AUTHOR]
- Subjects :
- ABDOMINAL surgery
ONLINE information services
MEDICAL databases
SOMATOMEDIN
COGNITION disorders
META-analysis
MEDICAL information storage & retrieval systems
ANESTHESIA
SYSTEMATIC reviews
PREOPERATIVE period
AGE distribution
SURGICAL complications
ACTIVITIES of daily living
RISK assessment
SEVERITY of illness index
DELIRIUM
POSTOPERATIVE period
QUESTIONNAIRES
DESCRIPTIVE statistics
RESEARCH funding
MEDLINE
DATA analysis software
BLOOD protein disorders
DISEASE risk factors
Subjects
Details
- Language :
- English
- ISSN :
- 08856230
- Volume :
- 38
- Issue :
- 6
- Database :
- Complementary Index
- Journal :
- International Journal of Geriatric Psychiatry
- Publication Type :
- Academic Journal
- Accession number :
- 164487669
- Full Text :
- https://doi.org/10.1002/gps.5942