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A day 1 hCG can differentiate non-viable intrauterine pregnancy and ectopic pregnancy following endometrial curettage.
- Source :
- Annals of Medical of Research; May2020, Vol. 27 Issue 5, p1422-1427, 6p
- Publication Year :
- 2020
-
Abstract
- Aim: The aim of the present study was to determine a cutoff level for a decrease in human chorionic gonadotropin (hCG) on postoperative day 1 to confirm intrauterine pregnancy (IUP) in patients who have undergone dilatation and curettage (D/C) with a presumptive diagnosis of nonviable pregnancy of unknown location (PUL). Material and Methods: This retrospective case-control study included patients who underwent D/C with a presumptive diagnosis of failing PUL between January 2010 and June 2015. Patients with failing PUL or confirmed to have an IUP were placed in Group 1 (n=164) and patients subsequently diagnosed with ectopic pregnancy were placed in Group 2 (n=19). In all patients, serum hCG levels were obtained on the day of D/C and on the following day. Results: The decline in serum hCG percentage on day 1 after D/C was 54.2% in patients with failing PUL/abortion and 14.3% in patients with ectopic pregnancy (p<0.001). A decrease in hCG of more than 35% was the most sensitive marker, with sensitivity, specificity, and positive and negative predictive values of 90%, 89%, 99%, and 50%, respectively. Conclusion: Determining post curettage day 1 hCG might aid clinicians in confirming failing IUP and in ruling out an ectopic pregnancy at an earlier date. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 26367688
- Volume :
- 27
- Issue :
- 5
- Database :
- Complementary Index
- Journal :
- Annals of Medical of Research
- Publication Type :
- Academic Journal
- Accession number :
- 164448985
- Full Text :
- https://doi.org/10.5455/annalsmedres.2019.12.785