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Chilblain-Like Lesions (CLL) Coinciding With the SARS-CoV-2 Pandemic in Children: A Systematic Review.
- Source :
- Journal of Cutaneous Medicine & Surgery; May2023, Vol. 27 Issue 3, p277-284, 8p
- Publication Year :
- 2023
-
Abstract
- Chilblain-like lesions (CLL) coinciding with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection have been described in the literature. Available reviews of the literature suggest that CLL are associated with younger age, an equal sex ratio, negative testing for SARS-CoV-2, and mild to no extracutaneous manifestations (ECM) associated with COVID-19 infection. This systematic review aims to provide a summary of reports of CLL associated with the early SARS-CoV-2 pandemic in children to clarify the prevalence, clinical characteristics, and resolution outcomes of these skin findings. Sixty-nine studies, published between May 2020 and January 2022, met inclusion criteria and were summarized in this review, representing 1,119 cases of CLL. Available data showed a slight male predominance (591/1002, 59%). Mean age was 13 years, ranging from 0 to 18 years. Most cases had no ECM (682/978, 70%). Overall, 70/507 (14%) of patients tested positive for COVID-19 using PCR and/or serology. In the majority the clinical course was benign with 355/415 (86%) of cases resolving, and 97/269 (36%) resolving without any treatment. This comprehensive summary of pediatric CLL suggests these lesions are rarely associated with COVID-19 symptoms or test positivity. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 12034754
- Volume :
- 27
- Issue :
- 3
- Database :
- Complementary Index
- Journal :
- Journal of Cutaneous Medicine & Surgery
- Publication Type :
- Academic Journal
- Accession number :
- 164441986
- Full Text :
- https://doi.org/10.1177/12034754231158074