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Left atrial strain analysis improves left ventricular filling pressures non-invasive estimation in the acute phase of Takotsubo syndrome.
- Source :
- European Heart Journal - Cardiovascular Imaging; Jun2023, Vol. 24 Issue 6, p699-707, 9p
- Publication Year :
- 2023
-
Abstract
- Aims The aim of our study is to assess the ability of left atrial (LA) strain values to improve left ventricular and diastolic pressure (LVEDP) non-invasive estimation as compared with traditional echocardiographic indexes in the acute phase of Takotsubo syndrome (TTS) and to predict adverse in-hospital outcomes in this population. Methods and results Consecutive TTS patients were prospectively enrolled. Left ventricular and diastolic pressure was measured at the time of catheterization. Transthoracic echocardiography was performed within 48 h from hospital admission. In-hospital complications (acute heart failure, death from any cause, and life-threatening arrhythmias) were collected. A total of 62 patients were analysed (72.2 ± 10.1 years, female 80%) and in-hospital complications occurred in 25 (40.3%). Left ventricular and diastolic pressure mean value was 24.53 ± 7.92 mmHg. Left atrial reservoir and pump strain values presented higher correlation with LVEDP (r −0.859, P < 0.001 and r −0.848, P < 0.001, respectively) in comparison with E / e ′ ratio, left atrial volume index (LAVi), and tricuspid regurgitation (TR) peak velocity. In addition, at receiver-operating characteristic curve analysis, LA reservoir and pump strain resulted to be better predictors of LVEDP above the mean of our population [0.909 (95% CI 0.818–0.999, P < 0.001) and 0.889 (95% CI 0.789–0.988, P < 0.001)], respectively] as compared with E / e ′ ratio, LAVi, and TR peak velocity. Finally, LA reservoir strain resulted to be an independent predictor of worse in-hospital outcomes, together with LVEDP and left ventricular ejection fraction (all P < 0.001). Conclusion In our study, lower LA reservoir and pump strain values were better predictors of LVEDP as compared with traditional echocardiographic indexes in the acute phase of TTS syndrome. Moreover, LA reservoir strain was an independent predictor of adverse in-hospital outcomes. [ABSTRACT FROM AUTHOR]
- Subjects :
- LEFT heart ventricle
ECHOCARDIOGRAPHY
CARDIAC catheterization
CAUSES of death
TAKOTSUBO cardiomyopathy
CONFIDENCE intervals
VENTRICULAR ejection fraction
MAJOR adverse cardiovascular events
TRICUSPID valve diseases
GLOBAL longitudinal strain
MANN Whitney U Test
FISHER exact test
DIASTOLIC blood pressure
RISK assessment
DIAGNOSTIC imaging
CORONARY angiography
HOSPITAL mortality
VENTRICULAR tachycardia
HOSPITAL care
DESCRIPTIVE statistics
CHI-squared test
RECEIVER operating characteristic curves
DATA analysis software
LOGISTIC regression analysis
STATISTICAL models
ARRHYTHMIA
LEFT heart atrium
LONGITUDINAL method
HEART failure
DISEASE risk factors
Subjects
Details
- Language :
- English
- ISSN :
- 20472404
- Volume :
- 24
- Issue :
- 6
- Database :
- Complementary Index
- Journal :
- European Heart Journal - Cardiovascular Imaging
- Publication Type :
- Academic Journal
- Accession number :
- 164368453
- Full Text :
- https://doi.org/10.1093/ehjci/jead045