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PET interim results could promptly select Follicular Lymphoma patients in need of maintenance therapy. Potential additional value of ctDNA.

Authors :
Jiménez‐Ubieto, A.
Poza, M.
López‐Pereira, P.
Figaredo, G.
Sarandeses, P.
Martin‐Muñoz, A.
Barrio, S.
Cortés, M.
Íñiguez, R.
Zamanillo, I.
Oliveira, A.
Rodríguez‐Izquierdo, A.
Baumann, T.
Revilla, E.
Gómez‐Rojas, S.
Pérez‐Segura, G.
Ayala, R.
Martínez‐López, J.
Source :
Hematological Oncology; Jun2023 Supplement S2, Vol. 41, p322-323, 2p
Publication Year :
2023

Abstract

PET interim results could promptly select Follicular Lymphoma patients in need of maintenance therapy. PET/CT SB EOT sb were predictive of relapse, with 2-years PFS 47% in PET/CT SB EOT sb (+) vs. 89% in PET/CT SB EOT sb (-) ( I p i <.001).On iPET/CT, 41 (34%) patients were PET/CT(+).The estimated 5 year-PFS at was 72% in patients with a negative iPET/CT versus 29% in those with a positive iPET/CT ( I p i < 0.001) (Figure 1a). B Conclusion: b Response assessment by PET/CT at mid-induction can identify FL patients at high risk of failure early on during first line ICT and is able promptly select patients in whom maintenance therapy could be avoided. [Extracted from the article]

Details

Language :
English
ISSN :
02780232
Volume :
41
Database :
Complementary Index
Journal :
Hematological Oncology
Publication Type :
Academic Journal
Accession number :
164231025
Full Text :
https://doi.org/10.1002/hon.3164_229